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The in vitro pharmacological characterization of naloxone benzoylhydrazone

✍ Scribed by Ilona P. Berzetei-Gurske; Angela White; Willma Polgar; Brian R. DeCosta; Gavril W. Pasternak; Lawrence Toll

Book ID
115890127
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
669 KB
Volume
277
Category
Article
ISSN
0014-2999

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Naloxone benzoylhydrazone (NalBzoH) has proved a valuable tool in the investigation of opioid receptor subtypes. In the present study, we have examined a series of derivatives of NalBzoH in which substitutions have been made on the benzoyl ring. Overall, we see dramatic effects on the binding affini