The in vitro metabolites of 2,4,6-trichlorophenol and their DNA strand breaking properties
β Scribed by Ursula Juhl; Konrad Blum; Irene Witte
- Book ID
- 113137271
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 636 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0009-2797
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π SIMILAR VOLUMES
Nonradiolabeled cells derived from animals or cell cultures can be examined in nucleotd gradients labeled with 4',6-diamidino-2-phenylindole to quantitate extremely low levels of DNA strand breaks and DNA superhelicity. In vitro: 4',6-Diamidino-2-phenylindole detection of DNA in nucleoid gradients r
2-Acetylaminofluorene (AAF) or trans-4-acetylaminostilbene (AAS) was orally or intraperitoneally administered to female Wistar rats. DNA from liver cells was analyzed for single-strand breaks by the alkaline elution assay. Only borderline effects were observed with doses (100 pmol/kg) used in animal