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The in vitro and in vivo profile of aclidinium bromide in comparison with glycopyrronium bromide

✍ Scribed by Gavaldà, Amadeu; Ramos, Israel; Carcasona, Carla; Calama, Elena; Otal, Raquel; Montero, José Luis; Sentellas, Sonia; Aparici, Monica; Vilella, Dolors; Alberti, Joan; Beleta, Jorge; Miralpeix, Montserrat

Book ID
124107238
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
698 KB
Volume
28
Category
Article
ISSN
1094-5539

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Alkylation of RNA by vinyl bromide metab
Alkylation of RNA by vinyl bromide metabolites in vitro and in vivo
✍ H. Ottenwälder; R. J. Laib; H. M. Bolt 📂 Article 📅 1979 🏛 Springer-Verlag 🌐 English ⚖ 374 KB

[1,2-14C]Vinyl bromide was incubated with rat liver microsomes, NADPH, and polyadenylic acid, polycytidylic acid, or RNA, respectively. Part of the adenosine moieties in RNA or in polyadenylic acid were alkylated and labelled 1,N6-ethenoadenosine structures were formed. Part of the cytidine moieties