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The In Vitro and In Vivo Antitumour Activities of Nitrosyl Ruthenium Amine Complexes

✍ Scribed by Osti, Renata Z.; Serrano, Fabiana A.; Paschoalin, Thaysa; Massaoka, Mariana H. S.; Travassos, Luiz R.; Truzzi, Daniela R.; Rodrigues, Elaine G.; Franco, Douglas W.


Book ID
120592279
Publisher
Commonwealth Scientific and Industrial Research Organisation Publishing
Year
2012
Tongue
English
Weight
789 KB
Volume
65
Category
Article
ISSN
0004-9425

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Key words: nephrotoxicity; platinum(II) complexes; ruthenium(III) complexes; rats. The nephrotoxicity of three platinum (CPL, KP734, KP735) and three ruthenium coordination complexes (KP418, KP692, KP1019) was tested in rats in comparison to cisplatin (CP). Renal functional changes (excretion of wa