The synergistic antitumor activity of mitomycin C (MMC) and cisplatin (DDP) against the gastric cancer cell lines MKN-28 and MKN-45 was assessed in vitro using the MTT assay. The synergism of the two agents was evaluated in terms of the interaction index (1.1.). The sequence of MMC followed by DDP s
The in vitro and in vivo Antitumor Activity of Vitamin C: K3 Combinations Against Prostate Cancer
โ Scribed by James M. Jamison; Jacques Gilloteaux; Henryk S. Taper; Pedro Buc Calderon; Laszlo Perlaky; Marc Thiry; Deborah R. Neal; James L. Blank; Robert J. Clements; Steve Getch; et al. et al.
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 8 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
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๐ SIMILAR VOLUMES
A new combined cancer chemotherapy regimen of mitomycin C (MMC) and cisplatin (DDP) showed synergistic antitumor activity against human gastric cancer xenografts St-40 and SC-1-NU in BALB/c nu/nu mice. The drugs were administered intraperitoneally at doses of 2 or 4 mg/kg for MMC and 3 or 6 mg/kg fo