The in situ generation of Ph3P=C(CF3)2. a facile one pot conversion of aldehydes to bis-trifluoromethyl olefins.

✍ Scribed by Donald J. Burton; Yoshio Inouye

• Book ID: 104246416
• Publisher: Elsevier Science
• Year: 1979
• Tongue: French
• Weight: 216 KB
• Volume: 20
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)95419-x

✦ Synopsis

The in situ reaction of triphenylphosphine with tetrakis(trifluoromethyl)-1,3-dithietane in the presence of aliphaticor aromatic aldehydes gives good to excellent yields of bis-trifluoromethyl olefins.

Although much recent work has produced useful synthetic routes to various types of fluoromethylene ylides2, little work has been reported on halogenated ylides other than methylene derivatives. Undoubtedly, the notable lack of success with these homologous ylides is a conse-