✦ LIBER ✦
The in situ generation of non-stabilized carbene complexes viaintramolecular acetylene insertion: A new two-alkyne annulation and a new preparation of γ-keto esters
✍ Scribed by William D. Wulff; Yao-Chang Xu
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 238 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Non-hetematom stabilized carbene complexes can be generated in solution by mild thermolysis (500 C) of 4hexynyl and Sheptynyl (methoxymethylene) complexes of chromium and tungsten pentacarbonyl. These intermediates react with acetylenes to give a new type of two-alkyne annulation product. In the absence of acetylenes, these intermediates can be trapped with methanol as their carbonylated pmducts which results in a new synthesis of pketo esters.