𝔖 Bobbio Scriptorium
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The importance of the C-terminal part of the alpha'-chain of C3b for its cleaage by factor 1

✍ Scribed by T.C. Farries; R.A. Harrison


Book ID
117326282
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
351 KB
Volume
35
Category
Article
ISSN
0161-5890

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Novel backbone-to-side chain and backbone-to-backbone cyclic analogues of substance P (SP) were prepared by solid-phase synthesis and screened for biological activity. An analogue containing a thioetherlactam ring between positions 9 and 11 showed an EC50 value of 20 nM toward the neurokinin 1 (NK-1