✦ LIBER ✦

The importance of MUC1 cellular localization in patients with breast carcinoma : An immunohistologic study of 71 patients and review of the literature

✍ Scribed by Jennifer J. Rahn; Laith Dabbagh; Manijeh Pasdar; Judith C. Hugh

Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 657 KB
Volume: 91
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(20010601)91:11<1973::aid-cncr1222>3.0.co;2-a

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✦ Synopsis

BACKGROUND.

The MUC1 mucin is present on the apical surface of normal secretory epithelia. In breast carcinoma, MUC1 expression is variable in amount and cellular localization, the significance of which is controversial. The authors undertook a detailed analysis of staining pattern combined with a comprehensive literature review to better understand the role of MUC1 in breast carcinoma.

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