The Importance of Lipid Research in Medicine — Requirements and Utilization of Results

✍ Scribed by Biró, G. ;Romics, L.

• Publisher: John Wiley and Sons
• Year: 1985
• Weight: 916 KB
• Volume: 87
• Category: Article
• ISSN: 0931-5985
• DOI: 10.1002/lipi.19850870108

✦ Synopsis

Authors review, according to literature data, the correlation between nutrition and serum lipids. Lipid metabolism is influenced by the total daily fat and cholesterol intake and by the PIS ratio although asignificant part of cholesterol is of endogenous origin. The decrease of fat consumption results in the decrease of the frequency of coronary andgenerallyof vascular diseases.The alterationsinthecoronaryvesselsaremoresevereinthecaseof higher serum cholesterol and triglyceride values. The inverse association of HDLcholesterol with the development of CHD is already a well-knownfact. It is very important that by these diseases several other risk factors are involved too and the exciting causes are of multiple kind. Prophylactic nutrition must be started in the young and at the same time efforts should be made to eliminate and decrease the correlating factors. The physiological role of polyunsaturated fatty acids is reported, which are considered as important but not sole favourable factors. The physiological effect of the trans-fatty acids, which develop by the hydrogenation of oils, is different from that of those cis-isomersoccurring in the organism but theirsignificancedependson the state of EFA supply. Fat consumption shows correlation with renal diseases and with malignant tumoun too. The fatty acid composition of human milk is highly important, for the present, infant formulae do not approach it. Fat consumption in Hungary is high: 31 kg per madper year which covers the 37 percent of daily energy intake. In the course of industrial processing of fats, processes with more favourable physiological effects have to be prefemd, e. g. transesterification. That's why the cooperation between physicians and experts of the industry has to be even closer in the future.