𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The importance of disulfide bridging

✍ Scribed by Harold E. Swaisgood

Book ID
113494508
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
58 KB
Volume
23
Category
Article
ISSN
0734-9750

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Structure–activity relationship studies
Structure–activity relationship studies of gomesin: Importance of the disulfide bridges for conformation, bioactivities, and serum stability
✍ Marcos A. Fázio; Vani X. Oliveira Jr.; Philippe Bulet; M. Terêsa M. Miranda; Sir 📂 Article 📅 2006 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 559 KB

## Abstract Gomesin is an antimicrobial peptide isolated from hemocytes of the Brazilian spider __Acanthoscurria gomesiana__ that contains two disulfide bridges Cys^2‐15^/Cys^6‐11^ and presents a β‐hairpin structure. To investigate the role of the disulfide bridges on gomesin conformation, bioactiv