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The importance of challenging phenylalanine (Phe) tolerance in patients with phenylketonuria (PKU)

✍ Scribed by Langley, Erica L.; Nedvidek, Julie A.; MacKenzie, Jennifer J.; Geraghty, Michael T.


Book ID
126815313
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
57 KB
Volume
47
Category
Article
ISSN
0009-9120

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The techniques of systems analysis have been applied to the metabolism of phenylalanine in healthy subjects and in phenylketonuria to derive a computer model. The model consists of seven compartments and four biological functions. Enzyme reactions are assumed to obey Michaelis-Menten kinetics. The c