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The implications of subunit interactions for the structure of the T cell receptor-CD3 complex

✍ Scribed by Frits Koning; W. Lee Maloy; John E. Coligan

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
1007 KB
Volume
20
Category
Article
ISSN
0014-2980

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πŸ“œ SIMILAR VOLUMES

Structural comparison of Ξ±/Ξ² and Ξ³/Ξ΄ T c
Structural comparison of Ξ±/Ξ² and Ξ³/Ξ΄ T cell receptor-CD3 complexes reveals identical subunit interactions but distinct cross-linking patterns of T cell receptor chains
✍ Joost van Neerven; John E. Coligan; Frits Koning πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 722 KB

## Abstract Here we compare the subunit interactions within the Ξ±/Ξ² and Ξ³/Ξ΄ T cell receptor‐CD3 (TcR‐CD3) complexes. By using different detergent solubilization protocols, subunit interactions can be defined within such cell surface receptor complexes. It was found that in both TcR‐CD3 complexes an