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The impact of temporal variability of biochemical markers PAPP-A and free β-hCG on the specificity of the first-trimester Down syndrome screening: a Croatian retrospective study

✍ Scribed by Dubravka Tišlarić-Medenjak; Ivana Zec; Ana-Maria Šimundić; Senka Sabolović-Rudman; Milan Kos; Željka Bukovec Megla

Book ID
115024874
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
247 KB
Volume
3
Category
Article
ISSN
1756-0500

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FIRST-TRIMESTER BIOCHEMICAL SCREENING FO
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✍ E. CASALS; A. FORTUNY; J. G. GRUDZINSKAS; Y. SUZUKI; B. TEISNER; C. COMAS; C. SA 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 550 KB

Biochemical screening for Down syndrome (DS) is well established in the second trimester of pregnancy, but there is little information available on its value in the first trimester. This study describes our preliminary results with biochemical screening for DS in the first trimester of pregnancy in

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In a population of 1467 women attending the 'G. Gaslini' Institute for antenatal care, we evaluated first-trimester risk screening for Down syndrome using the 'combined test' based on ultrasound measurement of nuchal translucency (NT), maternal serum pregnancy-associated plasma protein A (PAPP-A) an