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The impact of screening for propionic and methylmalonic acidaemia

โœ Scribed by James V. Leonard; Suresh Vijayaraghavan; John H. Walter


Publisher
Springer
Year
2003
Tongue
English
Weight
178 KB
Volume
162
Category
Article
ISSN
0340-6997

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The identification of (E)-2-methylglutac
โœ M. Duran; L. Bruinvis; D. Ketting; J. P. Kamerling; S. K. Wadman; R. B. H. Schut ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 456 KB ๐Ÿ‘ 1 views

The identification of (E)-2-methylglutaconic acid, a 'new' metabolite of isoleucine, is described. The substance was detected in urine samples from patients with propionic acidaemia, methylmalonic acidaemia and so-called P-ketothiolase deficiency; in the majority of cases together with N-tiglylglyci