The impact of PCR-generated recombination on diversity estimation of mixed viral populations by deep sequencing

Impact of demographic distribution and p

Impact of demographic distribution and population growth rate on haplotypic diversity linked to a disease gene and their consequences for the estimation of recombination rate: Example of a French Canadian population

✍ Frédéric Austerlitz; Evelyne Heyer 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 122 KB 👁 2 views

A disease gene introduced into a rapidly growing population by a single individual remains in strong linkage disequilibrium with the surrounding molecular markers. Mapping strategies taking advantage of this phenomenon allow increased mapping resolution as compared to pedigree analysis. Demographic