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The Impact of Long-Term In Vitro Expansion on the Senescence-Associated Markers of Human Adipose-Derived Stem Cells

โœ Scribed by Wan Kamarul Zaman Wan Safwani; Suzana Makpol; Somasundaram Sathapan; Kien Hui Chua


Book ID
113092765
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
438 KB
Volume
166
Category
Article
ISSN
0273-2289

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โœ Shivali Duggal; Jan E. Brinchmann ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 612 KB

## Abstract Human mesenchymal stem cells (hMSCs) may be used for therapeutic applications. Culture conditions such as the serum source may impact on cell quality and the onset of replicative senescence. We have examined the effect of culturing hMSCs in autologous serum (AS) versus fetal bovine seru