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The Impact of Lag Time on the Estimation of Pharmacokinetic Parameters. I. One-Compartment Open Model

โœ Scribed by Nadhamuni G. Nerella; Lawrence H. Block; Patrick K. Noonan

Book ID
110380299
Publisher
Springer US
Year
1993
Tongue
English
Weight
917 KB
Volume
10
Category
Article
ISSN
0724-8741

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โœ I. McMillan; Ch.E. Minder ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 420 KB

Methods of parameter estimation for nonlinear models have generally been based on appropriate least squares procedures. The authors have presented previously, for the one compartment open model, a marginal likelihood approach which obviates some of the difhcuhies encountered in the nonlinear least s