The impact of iatrogenic gastroschisis on pulmonary maturation in the fetal rabbit models of congenital diaphragmatic hernia
β Scribed by Gong Chen; Shan Zheng; Xian Min Xiao; Yi Luo
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 395 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0179-0358
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The incidence of congenital diaphragmatic hernia (CDH) is 1:1,207-5,000, and the condition is associated with high mortality and morbidity, attributed principally to associated pulmonary hypoplasia. Repairing the diaphragmatic defect by antenatal surgery has high mortality, mainly due to premature l
## Abstract ## Background __In utero__ tracheal occlusion (TO) has been developed to improve the lung hypoplasia associated with congenital diaphragmatic hernia (CDH). However, although TO stimulates fetal lung growth, it results in a decrease of alveolar type II cells (ATII) and surfactant produc