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The impact of depression on cognition varies by APOE4 status

✍ Scribed by Dentino, Andrew; Hall, James; Barber, Robert; Doody, Rachelle; Royall, Donald; O'Bryant, Sidney

Book ID
123204932
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
54 KB
Volume
7
Category
Article
ISSN
1552-5260

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## Abstract ## Objective The Ξ΅4 allele, a variant of the apolipoprotein E (ApoE) gene, is the most prominent genetic risk factor for sporadic, non‐familial Alzheimer's disease (AD) currently known. We investigated the impact of the ApoE‐Ρ4 status on cognitive performance at repeated test administr