The impact of aromatase inhibitor therapy on bone turnover, cortical bone growth and vertebral morphology in peripubertal boys with idiopathic short stature

Vertebral morphology in aromatase inhibi

Vertebral morphology in aromatase inhibitor–treated males with idiopathic short stature or constitutional delay of puberty

✍ Matti Hero; Sanna Toiviainen-Salo; Sanna Wickman; Outi Mäkitie; Leo Dunkel 📂 Article 📅 2010 🏛 American Society for Bone and Mineral Research 🌐 English ⚖ 222 KB

## Abstract Aromatase inhibitors (AIs), blockers of estrogen biosynthesis, delay bone maturation and therefore are used increasingly to promote growth in children and adolescents with growth disorders. The effects of treatment on skeletal health are largely unknown. Since estrogen deficiency is ass