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The Immunosuppressive Activity of Polymeric Micellar Formulation of Cyclosporine A: In VitroandIn VivoStudies

✍ Scribed by Samar Hamdy; Azita Haddadi; Anooshirvan Shayeganpour; Aws Alshamsan; Hamidreza Montazeri Aliabadi; Afsaneh Lavasanifar


Book ID
111767712
Publisher
American Association of Pharmaceutical Scientists
Year
2011
Tongue
English
Weight
594 KB
Volume
13
Category
Article
ISSN
1550-7416

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Cyclophilin binds to the region of cyclo
✍ ValΓ©rie F. J. Quesniaux; Max H. Schreier; Roland M. Wenger; Peter C. Hiestand; M πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 784 KB

Although several cytosolic proteins including calmodulin and cyclophilin have been shown to bind cyclosporine, the direct involvement of these proteins in the immunosuppressive activity of cyclosporine remains to be established. In the present study, a quantitative immunoassay for cyclophilin was de