The immune response to citrullinated proteins in patients with rheumatoid arthritis
β Scribed by Allan S. Wiik
- Book ID
- 110625701
- Publisher
- Humana Press Inc
- Year
- 2007
- Tongue
- English
- Weight
- 86 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1080-0549
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## Abstract ## Objective Rheumatoid arthritis (RA) is considered to be a prototypical autoimmune disease. However, the autoantigens that play an important role in the development of RA remain unclear. The aim of this study was to investigate whether T cells specific for citrullinated epitopes from
## Abstract The immune response was studied in 21 patients with rheumatoid arthritis. Eleven had been randomly assigned to receive cyclophosphamide, 50 to 75 mg/day, and 10 to receive a placebo. Immunologic responsiveness was assessed by delayed hypersensitivity skin testing, immunoglobulin levels,