Content: BASIC IMMUNOLOGY --
Perspective on Immunity --
Introduction to the Immune Response --
Cells and Tissues of the Immune Response --
Innate Immunity --
B Cell Receptor Structure and Effector Function --
Antigen-Antibody Interaction --
Exploiting Antigen-Antibody Interaction --
The Immunoglobulin Genes --
The Humoral Response: B Cell Development and Activation --
The Major Histocompatibility Complex --
Antigen Processing and Presentation --
T Cell Receptor: Structure of its Proteins and Genes --
T Cell Development --
T Cell Activation --
T cell differentiation and effector function --
Immune Tolerance in the Periphery --
Cytokines and their Receptors --
Bridging Innate and Specific Immunity: NK, gd T and NKT cells --
Complement --
Mucosal and Cutaneous Immunity --
Comparative Immunology --
CLINICAL IMMUNOLOGY --
Immunity to Pathogens --
Vaccines and Clinical Immunization --
Primary Immunodeficiencies --
HIV and Acquired Immunodeficiency Syndrome --
Tumor Immunology --
Transplantation --
Allergy and Hypersensitivity --
Autoimmune Disease --
Glossary --
Appendices --
Index --
Abbreviations.
Abstract: The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. * Current and thorough 30 chapter reference reviewed by luminaries in the field * Unique single voice' ensures consistency of definitions and concepts * Comprehensive and elegant illustrations bring key concepts to life * Provides historical context to allow fuller understanding of key issues * Introductory chapters 1-4 serve as an Immunology Primer' before topics are discussed in more detail * Includes a CD-ROM containing all the figures and plates appearing in the book