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The identification of peptide sequences of human chorionic gonadotropin containing a conformational epitope

✍ Scribed by Vernon C. Stevens; Wen-Shiung Chou; John E. Powell; Arthur C. Lee; Jeffrey Smoot

Book ID
104176839
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
444 KB
Volume
12
Category
Article
ISSN
0165-2478

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The beta-subunit of the human chorionic gonadotropin (hCG) hormone, which is believed to be related to certain types of cancer, contains three hairpin-like fragments. To investigate the role of beta-hairpin formation in the early stages of the hCGbeta folding, a 28-residue peptide with the sequence