The identification of ceramides and glyceryl ethers in unsaponifiable lipid of human aorta

✍ Scribed by Max Royer; J.Lindsley Foote

• Publisher: Elsevier Science
• Year: 1971
• Tongue: English
• Weight: 853 KB
• Volume: 7
• Category: Article
• ISSN: 0009-3084
• DOI: 10.1016/0009-3084(71)90005-3

✦ Synopsis

Unsaponifiable material from a lipid fraction isolated from atherosclerotic human aorta, contained cerebrosides, which had been previously identified, ceramides, and glycerol ethers, as well as other, still unidentified, substances. Identification of the ceramides and glycerol ethers was made primarily by gas-liquid chromatography and gas-liquid chromatography-mass spectrometry.

Ceramides were present with the fatty acids 16:0, 23:0, 24:0, and 24:1. Other fatty acids were found which were probably primarily associated with ceramides. These acids were 18:0, 18:1, 20:0, 22:0, and 25:0.

The glycerol ethers were 1-glycerol ethers of the fatty alcohols 16:0, 18:0, and 18:1. Glycerol ethers may well have been formed from diacylglycerol ethers during the isolation procedure.