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The hypoxia-inducible factor-1α is a negative factor for tumor therapy

✍ Scribed by Unruh, Annika; Ressel, Anke; Mohamed, Hamid G; Johnson, Randall S; Nadrowitz, Roger; Richter, Eckart; Katschinski, Dörthe M; Wenger, Roland H


Book ID
110067498
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
208 KB
Volume
22
Category
Article
ISSN
0950-9232

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Expression of hypoxia-inducible factor-1
✍ Toshio Kuwai; Yasuhiko Kitadai; Shinji Tanaka; Seiji Onogawa; Norimasa Matsutani 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 398 KB

## Abstract HIF‐1 is reported to transactivate expression of VEGF, which is an important angiogenic factor. To determine whether HIF‐1α plays a role in angiogenesis through its regulation of VEGF, we examined expression of HIF‐1α and its relation to clinicopathologic features, VEGF expression and p