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The Hypocretin/Orexin System: Implications for Drug Reward and Relapse

✍ Scribed by Plaza-Zabala, Ainhoa; Maldonado, Rafael; Berrendero, Fernando


Book ID
113093947
Publisher
Springer
Year
2012
Tongue
English
Weight
372 KB
Volume
45
Category
Article
ISSN
0893-7648

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The blood-brain barrier (BBB) limits the distribution of systemically administered therapeutics to the central nervous system (CNS). Intranasal delivery is a noninvasive method that targets drugs to the brain and spinal cord along olfactory and trigeminal neural pathways, bypassing the BBB and minim