Intranasal drug targeting of hypocretin-
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Shyeilla V. Dhuria; Leah R. Hanson; William H. Frey II
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Article
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2009
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John Wiley and Sons
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English
⚖ 210 KB
👁 1 views
The blood-brain barrier (BBB) limits the distribution of systemically administered therapeutics to the central nervous system (CNS). Intranasal delivery is a noninvasive method that targets drugs to the brain and spinal cord along olfactory and trigeminal neural pathways, bypassing the BBB and minim