The aerobic fed-batch production of recombinant human growth hormone (rhGH) by Escherichia coli was studied. The goal was to determine the production and protein degradation pattern of this product during fed-batch cultivation and to what extent scale differences depend on the presence of a fed-batc
The Hyperexponential Growth of the Human Population on a Macrohistorical Scale
β Scribed by S.D. VARFOLOMEYEV; K.G. GUREVICH
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 216 KB
- Volume
- 212
- Category
- Article
- ISSN
- 0022-5193
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β¦ Synopsis
A qualitative comparison of human population dynamics with some other biological populations growth in free regime is given in this paper along with a quantitative description of human population growth in the last 2000 years. It is shown that human population growth law is very di!erent from the growth laws of other populations: all biological populations grow according to exponential law, whereas the human population grows according to hyperexponential law which essentially moves ahead of the exponential one. It is found that unlike cell populations, the di!erential equation of rate of human population growth is of second order. This phenomenon can be described due to accelerating function which grows simultaneously with human population number. An analytical hyperexponential equation, which allows to describe dynamics of human population, was obtained.
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