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The human T cell antigen receptor repertoire: skewed use of Vβ gene families by CD8+ cells

✍ Scribed by G. R. CLARKE; C. A. HUMPHREY; F. C. LANCASTER; A. W. BOYLSTON


Book ID
108698565
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
430 KB
Volume
96
Category
Article
ISSN
0009-9104

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The antigenic specificity of the majority of T lymphocytes in the peripheral blood is determined by the combination of a and p variable region chains present in the T cell receptor complex. Currently, the Vp chains are grouped into 25 families. Historically, determination of Vp usage has relied on d