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The human polysaccharide- and protein-specific immune response to Streptococcus pneumoniae is dependent on CD4+ T lymphocytes, CD14+ monocytes, and the CD40–CD40 ligand interaction

✍ Scribed by Moens, Leen; Wuyts, Greet; Boon, Louis; den Hartog, Marcel T.; Ceuppens, Jan L.; Bossuyt, Xavier


Book ID
119280979
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
169 KB
Volume
122
Category
Article
ISSN
1097-6825

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B cell differentiation depends on cellular interactions with T lymphocytes and monocytes via adhesion molecules (AM). In order to characterize AM which are required for B cell differentiation immunoglobulin production using unseparated peripheral blood mononuclear cells (PBMC) was studied. Unstimula