## Abstract Human papillomavirus (HPV) infection is associated with cervical cancer. The E2 and E1 papillomavirus proteins are expressed at the early stage of infection and regulate DNA replication. The E2 protein activates and represses transcription from different HPVs promoters. At some stage wh
✦ LIBER ✦
The Human Papillomavirus Type 18 (HPV18) Replication Protein E1 Is a Transcriptional Activator When Interacting with HPV18 E2
✍ Scribed by Caroline Demeret; Sylvain Goyat; Moshe Yaniv; Françoise Thierry
- Book ID
- 112271908
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 370 KB
- Volume
- 242
- Category
- Article
- ISSN
- 0042-6822
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HPV 18 is associated with 2 divergent phenotypes: (i) aggressive cervical cancer and a preponderance of cancer relative to cervical intra-epithelial neoplasia (CIN) and (ii) benign warty lesions of the cervix. The €2 gene of HPV 18 encodes a regulatory protein that represses viral oncogene transcrip
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