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The human mitochondrial replication fork in health and disease

✍ Scribed by Sjoerd Wanrooij; Maria Falkenberg


Book ID
113484561
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
846 KB
Volume
1797
Category
Article
ISSN
0005-2728

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## Abstract The organisation of mammalian mitochondrial DNA (mtDNA) is more complex than usually assumed. Despite often being depicted as a simple circle, the topology of mtDNA can vary from supercoiled monomeric circles over catenanes and oligomers to complex multimeric networks. Replication of mt