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The HUman MicroNucleus Project—An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans

✍ Scribed by Michael Fenech; Nina Holland; Wushou P Chang; Errol Zeiger; Stefano Bonassi

Book ID
114396594
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
760 KB
Volume
428
Category
Article
ISSN
0027-5107

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The current method for scoring micronuclei as a measure of genetic damage rate in peripheral blood cells is to enumerate this end point in cytokinesis-blocked binucleated cultured lymphocytes. However, one can expect that, due to chronic exposure to genotoxins or inherent genetic instability, micron