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The Human Leukocyte Antigen Region and Colorectal Cancer Risk

โœ Scribed by Mirjam M. de Jong; Marijke Niens; Ilja M. Nolte; Gerard J. te Meerman; Winette T. A. van der Graaf; Marcel J. Mulder; Gerrit van der Steege; Marcel Bruinenberg; Michael Schaapveld; Rolf H. Sijmons; Robert M. W. Hofstra; Elisabeth G. E. de Vries; Jan H. Kleibeuker

Book ID
106320450
Publisher
Springer
Year
2005
Tongue
English
Weight
114 KB
Volume
48
Category
Article
ISSN
0012-3706

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โœ Bateman, A. C.; Howell, W. M. ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 176 KB

Human leukocyte antigens (HLAs) are widely expressed cell surface molecules which present antigenic peptides to T-lymphocytes, thus modulating the immune response. The efficiency of peptide presentation by HLAs is dependent on the extreme polymorphism in the HLA-encoding loci within the major histoc