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The human kininogen gene (KNG) mapped to chromosome 3q26-qter by analysis of somatic cell hybrids using the polymerase chain reaction

✍ Scribed by Dunne Fong; David I. Smith; Wang-Ting Hsieh

Publisher: Springer
Year: 1991
Tongue: English
Weight: 387 KB
Volume: 87
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00204179

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✦ Synopsis

Kinins, peptide products of kininogens, may be involved in hypertensive and diabetic diseases, and inflammatory disorders. The human kininogen gene (KNG) has been mapped to chromosome 3, using a panel of human-hamster somatic cell hybrids by polymerase chain reaction of hybrid DNA with gene-specific primers. KNG was further assigned to 3q26-3qter, using DNA from a second panel of chromosome 3 deletion mapping cell hybrids.

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