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The human insulin-like growth factor II gene contains two development-specific promoters

โœ Scribed by P. de Pagter-Holthuizen; M. Jansen; F.M.A. van Schaik; R. van der Kammen; C. Oosterwijk; J.L. Van den Brande; J.S. Sussenbach


Book ID
115918940
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
620 KB
Volume
214
Category
Article
ISSN
0014-5793

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Promoter-specific insulin-like growth fa
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Insulin-like growth factor 2 (IGF2) gene imprinting has been demonstrated to be promoter-specific, in that expression from the P1 promoter is biallelic whereas that from the P2-P4 promoters is monoallelic. In the present study, in order to investigate IGF2 gene imprinting status at the cellular leve