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The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects

✍ Scribed by Karin Hochrainer; Herbert Mayer; Ulrike Baranyi; BerndR. Binder; Joachim Lipp; Renate Kroismayr


Book ID
116981345
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
872 KB
Volume
85
Category
Article
ISSN
0888-7543

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We have identified a novel gene encoding a protein designated DLEC (dendritic cell lectin), which is a type II membrane glycoprotein of 213 amino acids and belongs to the human calcium-dependent (C-type) lectin family. The cytoplasmic tail of DLEC lacks consensus signaling motifs and its extracellul