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The human growth hormone receptor gene — characterisation of the liver-specific promoter

✍ Scribed by Caroline A Rivers; Michael R Norman


Book ID
117464374
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
826 KB
Volume
160
Category
Article
ISSN
0303-7207

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To assess the evolutionary importance of nonallelic (or interlocus) gene conversion for the highly polymorphic human growth hormone (GH1) gene promoter, sequence variation in this region was studied in four different ethnic groups. For 14 SNPs in the proximal GH1 promoter (535 bp), 60 different hapl