The human colon cancer cell line Caco-2 spontaneously differentiates to an enterocyte-like cell after confluence under standard culture conditions. This is characterized by polarization of the cell monolayer with the appearance of tight junctions, a brush border membrane and expression of brushborde
The human colon cancer cell line CaCo-2 produces secretory components during enterocytic differentiation
β Scribed by Hirata, Makoto ;Bamba, Tadao ;Hosoda, Shiro
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 727 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0435-1339
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We previously reported that the enterocytic differentiation of human colonic Caco-2 cells correlated with down-regulation of fibronectin (FN) and laminin (LN), two extracellular matrix components interacting with cell surface integrin receptors. We now investigated whether Caco-2 cell differentiatio
The activity of β€-galactoside β£2,6-sialyltransferase (ST6Gal.1), the enzyme responsible for the addition of sialic acid in β£2,6-linkage to N-acetyllactosaminic (Galβ€1,4GlcNAc) units of glycoconjugates, is increased in the vast majority of colon cancer specimens, and a positive correlation with an in