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The HPV E7 oncoprotein inhibits tumor necrosis factor α-mediated apoptosis in normal human fibroblasts

✍ Scribed by Thompson, David Alan; Zacny, Valerie; Belinsky, Glenn Scott; Classon, Marie; Jones, Dana Leanne; Schlegel, Robert; Münger, Karl

Book ID: 110064758
Publisher: Nature Publishing Group
Year: 2001
Tongue: English
Weight: 342 KB
Volume: 20
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1204483

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## Objective: To investigate the effects of the antiinflammatory cytokines interleukin-4 (il-4), il-10, and il-13 on tumor necrosis factor alpha (tnfalpha)-induced prostaglandin e2 (pge2) release in the cellular signaling cascade on human osteoarthritis (oa) synovial fibroblasts. ## Methods: Huma