The ‘hot cross bun’ sign in the patients with spinocerebellar ataxia
✍ Scribed by Y.-C. Lee; C.-S. Liu; H.-M. Wu; P.-S. Wang; M.-H. Chang; B.-W. Soong
- Book ID
- 111065859
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 134 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1351-5101
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Spinocerebellar ataxia 8 (SCA8) is caused by a CTG repeat expansion in an untranslated region of a recently cloned gene on 13q21. The pathogenic role of this trinucleotide repeat was evaluated by examining 154 Finnish ataxia patients and 448 controls. Expansions ranging from 100 to 675 repeats were