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The homeodomain transcription factor Cdx1 reduces the growth of human colon cancer cells by altering cyclin D levels

✍ Scribed by Lynch, John P.; Yang, Donald; Suh, EunRan; Traber, Peter G.

Book ID: 122750613
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 366 KB
Volume: 118
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(00)85569-9

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## Abstract Studies have shown that nonsteroidal antiinflammatory drugs (NSAIDs) reduce the risk of and mortality from a variety of cancers. Although cyclooxygenase (COX)‐dependent and ‐independent pathways may be involved, the mechanisms responsible for these effects remain unknown. In our study,