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The HLA system in Inupiat and central Yupik Alaskan eskimos

✍ Scribed by Hansen, John A.; Lanier, Anne P.; Nisperos, Brenda; Mickelson, Eric; Dahlberg, Steve


Book ID
122572438
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
791 KB
Volume
16
Category
Article
ISSN
0198-8859

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## Abstract Loss of heterozygosity (LOH) is a major mechanism for inactivation of tumor‐suppressor genes and has been observed in various solid tumors and lymphomas. The human leukocyte antigen (HLA) region is located at chromosome band 6p21.3, and loss or alteration of this region may provide tumo