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The HLA DQB 1*0502 allele is neutrally associated with insulin-dependent diabetes mellitus in the Sardinian population

✍ Scribed by F. Muntoni; M. Congia; F. Cucca; P. Cossu; S. Porcu; F. Frau; M. Arnone; M. Songini; S. Muntoni; A. Gao; M. Pirastu


Book ID
115096198
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
371 KB
Volume
39
Category
Article
ISSN
0001-2815

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πŸ“œ SIMILAR VOLUMES


Both DQA1 and DQB1 genes are implicated
✍ D. A. Cavan; K. H. Jacobs; M. A. Penny; M. A. Kelly; C. Mijovic; D. Jenkins; J. πŸ“‚ Article πŸ“… 1993 πŸ› Springer 🌐 English βš– 663 KB

Inherited susceptibility to Type 1 (insulin-dependent) diabetes mellitus is partly determined by HLA genes. It has been suggested that protection from disease may be conferred by HLA-DQB1 genes which encode molecules with aspartate at position 57. We investigated the contributions of HLA-DRB1, DQA1