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The Histone Deacetylase Inhibitor Sodium Butyrate Promotes Cell Death and Differentiation and Reduces Neurosphere Formation in Human Medulloblastoma Cells

✍ Scribed by Nör, Carolina; Sassi, Felipe A.; Farias, Caroline Brunetto; Schwartsmann, Gilberto; Abujamra, Ana Lucia; Lenz, Guido; Brunetto, Algemir Lunardi; Roesler, Rafael


Book ID
120447955
Publisher
Springer
Year
2013
Tongue
English
Weight
531 KB
Volume
48
Category
Article
ISSN
0893-7648

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## Abstract Aberrant janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling is involved in the oncogenesis of several cancers. Suppressors of cytokine signaling (SOCS) genes and SH2‐containing protein tyrosine phosphatase 1 (SHP1) proteins, which are negative regulator