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The histamine H2 receptor stimulates c-fos transcription and cell proliferation via a map kinase-dependent mechanism

✍ Scribed by Wang, L.; Wang, M.; Todisco, A.; Suzuki, T.; del Valle, J.


Book ID
122641738
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
184 KB
Volume
114
Category
Article
ISSN
0016-5085

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## Abstract Activation of __c‐fos__ in brain is related to coupling of neuronal activity to gene expression, but also to pathological conditions such as seizures or excitotoxicity‐induced cell death. Glutamate activates __c‐fos__ in neurons through the calcium‐dependent phosphorylation of CREB by E