The histamine analogue impentamine discriminates between peripheral and brain histamine H3 receptors
β Scribed by LEURS, R; KATHMANN, M; VOLLINGA, R; MENGE, W; SCHLICKER, E; TIMMERMAN, H
- Book ID
- 123008300
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 119 KB
- Volume
- 31
- Category
- Article
- ISSN
- 1043-6618
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Following up h e finQng that the non-imidazole drug clozapine shows a considerable histamine H3 receptor antagonistic activiryl 1.21 , a scrim of analogues and metabolites (clorapinc-N-oxide. and N-desmcthylclozapine) were tested for thcir affinity towards thc H3 receptor using the radiolabelled H,