The Hippocampus from Cells to Systems: Structure, Connectivity, and Functional Contributions to Memory and Flexible Cognition

✍ Scribed by Deborah E. Hannula, Melissa C. Duff (eds.)

• Publisher: Springer International Publishing
• Year: 2017
• Tongue: English
• Leaves: 587
• Edition: 1
• Category: Library

✦ Synopsis

The hippocampus has long been considered a critical substrate in the neurobiology, neuropsychology, and cognitive neuroscience of memory. Over the past few decades, a number of ground-breaking theoretical and methodological advances have radically enhanced our understanding of the structure and function of the hippocampus and revolutionized the neuroscientific study of memory. Cutting across disciplines and approaches, these advances offer novel insights into the molecular and cellular structure and physiology of the hippocampus, the role of hippocampus in the formation, (re)consolidation, enhancement, and retrieval of memory across time and development, and permit investigators to address questions about how the hippocampus interacts, functionally and anatomically, with other neural systems in service of memory. In addition, recent investigations also suggest that the mechanistic properties and functional processing features of the hippocampus permit broader contributions to cognition, beyond memory, to the domains of attention, decision-making, language, social cognition, and a variety of other capacities that are critical for flexible cognition and behavior. These advances have profound implications for the neurobiology and cognitive neuroscience of hippocampus dependent cognition and for the numerous psychiatric and neurological diseases and disorders for which hippocampal pathology is a hallmark such as Alzheimer’s disease and schizophrenia.
The goal of this book is to bring together in a single source an integrated review of these advances providing state of the art treatment on the structure and function of the hippocampus. Contributors will examine the hippocampus from a variety of levels (from cells to systems) using a wide range of methods (from neurobiological approaches in non-human animals to neuroimaging and neuropsychological work in humans).

✦ Table of Contents

Front Matter....Pages i-x
Front Matter....Pages 1-1
The Nonhuman Primate Hippocampus: Neuroanatomy and Patterns of Cortical Connectivity....Pages 3-36
Human Hippocampal Theta Oscillations: Distinctive Features and Interspecies Commonalities....Pages 37-67
Elements of Information Processing in Hippocampal Neuronal Activity: Space, Time, and Memory....Pages 69-94
Hippocampal Neurogenesis and Forgetting....Pages 95-121
Manipulating Hippocampus-Dependent Memories: To Enhance, Delete or Incept?....Pages 123-137
Front Matter....Pages 139-139
Hippocampal Development: Structure, Function and Implications....Pages 141-166
Age-Related Differences in the Human Hippocampus: Behavioral, Structural and Functional Measures....Pages 167-208
Physical Activity and Cognitive Training: Impact on Hippocampal Structure and Function....Pages 209-243
Hippocampal Contributions to Declarative Memory Consolidation During Sleep....Pages 245-280
Beyond Long-Term Declarative Memory: Evaluating Hippocampal Contributions to Unconscious Memory Expression, Perception, and Short-Term Retention....Pages 281-336
Memory, Relational Representations, and the Long Reach of the Hippocampus....Pages 337-366
Front Matter....Pages 367-367
How Hippocampal Memory Shapes, and Is Shaped by, Attention....Pages 369-403
The Hippocampus and Memory Integration: Building Knowledge to Navigate Future Decisions....Pages 405-437
Escaping the Past: Contributions of the Hippocampus to Future Thinking and Imagination....Pages 439-465
Distinct Medial Temporal Lobe Network States as Neural Contexts for Motivated Memory Formation....Pages 467-501
Hippocampal Contributions to Language Use and Processing....Pages 503-536
The Hippocampus and Social Cognition....Pages 537-558
Dynamic Cortico-hippocampal Networks Underlying Memory and Cognition: The PMAT Framework....Pages 559-589

✦ Subjects

Neurosciences;Neurobiology;Cognitive Psychology